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  • Nanotechnology meets oncology [Elektronski vir] : nanomaterials in brain cancer research, diagnosis and therapy
    Zottel, Alja ; Videtič Paska, Alja, 1980- ; Jovchevska, Ivana
    Advances in technology of the past decades led to development of new nanometer scale diagnosis and treatment approaches in cancer medicine leading to establishment of nanooncology. Inorganic and ... organic nanomaterials have been shown to improve bioimaging techniques and targeted drug delivery systems. Their favorable physico-chemical characteristics, like small sizes, large surface area compared to volume, specific structural characteristics, and possibility to attach different molecules on their surface transform them into excellent transport vehicles able to cross cell and/or tissue barriers, including the blood-brain barrier. The latter is one of the greatest challenges in diagnosis and treatment of brain cancers. Application of nanomaterials can prolong the circulation time of the drugs and contrasting agents in the brain, posing an excellent opportunity for advancing the treatment of the most aggressive form of the brain cancer-glioblastomas. However, possible unwanted side-effects and toxicity issues must be considered before final clinical translation of nanoparticles.
    Vir: Materials [Elektronski vir]. - ISSN 1996-1944 (Vol. 12, no. 10, 2019, str. 1-28)
    Vrsta gradiva - e-članek ; neleposlovje za odrasle
    Leto - 2019
    Jezik - angleški
    COBISS.SI-ID - 34313945

    Povezava(-e):

    https://www.mdpi.com/1996-1944/12/10/1588
    Repozitorij Univerze v Ljubljani – RUL
    DOI

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