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  • High-dose cholecalciferol supplementation for vitamin D deficiency in haemodialysis patients
    Jakopin, Eva ...
    Vitamin D deficiency, which is a recognized problem in haemodialysis (HD) patients, has been associated with higher all-cause mortality. There are no guidelines concerning vitamin D supplementation ... in HD patients. This study aimed to assess the effects of once-monthly supplementation with high-dose cholecalciferol (vitamin D3) in HD patients. Patients with 25-hydroxyvitamin D (25[OH]D) levels below 75 nmol/l received 40 000 IU of cholecalciferol once-monthly for 3 months in succession. Every 4 months, 25(OH)D levels were measured and, based on the findings, cholecalciferol therapy was continued for another cycle if necessary. Six cycles were completed in the 24-month study period. The majority of HD patients had mild or severe vitamin D deficiency at baseline. Monthly supplementation with cholecalciferol at 40 000IU was well tolerated, safe and inexpensive. The treatment regime was effective for vitamin D insufficiency but did not prove to be enough to restore 25(OH)D levels in HD patients with mild or severe vitamin D deficiency.
    Vir: Journal of international medical research. - ISSN 0300-0605 (Vol. 39, no. 3, 2011, str. 1099-1106)
    Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasle
    Leto - 2011
    Jezik - angleški
    COBISS.SI-ID - 3998015

    Povezava(-e):

    http://www.jimronline.net/content/full/2011/103/1676.pdf

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