VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Prediction of human blastocyst development from morulas with delayed and/or incomplete compaction
    Ivec, Martin ; Kovačič, Borut ; Vlaisavljević, Veljko
    Objective: To determine the influence of delayed compaction and fragmentation on the developmental capacity of morulas. Design: Prospective study. Setting: University IVF center. Patient(s): ... Intracytoplasmic sperm injection (ICSI) cycles with compact embryos on day 4 or day 5. Intervention(s): The embryos were divided into day 4 (n = 329) and day 5 (n = 256) morulas and graded I, II, or III, according to the percentage of fragmentation (<5%, 5%-20%, or >20 %). The embryos were measured using Cronus3 software. Main Outcome Measurement(s): Blastocyst development rate, blastocoel expansion rate, and optimal blastocyst rate. In an optimal blastocyst: surface area, trophectoderm cell number, inner cell mass (ICM) surface area, ICM volume and ICM shape. Result(s): Day 4 morulas in classes I-III developed into optimal blastocysts in 57.4%, 50%, and 35.6% of the total, respectively, and day 5 morulas in classes I-III in 43.3%, 29.1%, and 13.6% of the total, respectively. A negative association was identified between the amount of morula fragmentation, the blastocyst ICM size, and the number of trophectoderm cells. A delay of 1 day in compaction was associated with a reduced ICM volume. Conclusion(s): The measurement of compaction timing and cytoplasmic loss in morulas assists in predicting their ability to develop into optimal blastocysts.
    Vir: Fertility and sterility. - ISSN 0015-0282 (Vol. 96, no. 6, Dec. 2011, str. 1473-1478.e2)
    Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasle
    Leto - 2011
    Jezik - angleški
    COBISS.SI-ID - 4067391

    Povezava(-e):

    http://www.sciencedirect.com/science/article/pii/S0015028211025143
    DOI

vir: Fertility and sterility. - ISSN 0015-0282 (Vol. 96, no. 6, Dec. 2011, str. 1473-1478.e2)
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