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Simple cystatin C formula for estimation of glomerular filtration rate in overweight patients with diabetes mellitus type 2 and chronic kidney diseaseBevc, Sebastjan ...In clinical practice the glomerular filtration rate (GFR) is estimated from serum creatinine-based equations like the Cockcroft-Gault formula (C&G) and Modification of Diet in Renal Disease formula ... (MDRD). Recently, serum cystatin C-based equations, the newer creatinine formula (The Chronic Kidney Disease Epidemiology Collaboration formula (CKD-EPI)), and equation that use both serum creatinine and cystatin C (CKD-EPI creatinine & cystatin formula) were proposed as new GFR markers. Present study compares serum creatinine-based equations, combined (including both serum creatinine and cystatin C) equation, and serum simple cystatin C formula (100/serum cystatin C) against 51CrEDTA clearance in 113 adult overweight Caucasians with diabetes mellitus type 2 (DM2) and chronic kidney disease (CKD). The results of present study demonstrated that the simple cystatin C formula could be a useful tool for the evaluation of renal function in overweight patients with DM2 and impaired kidney function in daily clinical practice in hospital and especially in outpatients. Despite the advantages of the simple cystatin C formula, cystatin C-based equations cannot completely replace the "gold standard" for estimation of the GFR in a population of DM2 patients with CKD, but may contribute to a more accurate selection of patients requiring such invasive and costly procedures.Vir: Experimental Diabetes Research (Print). - ISSN 1687-5214 (Vol. 2012, 2012, article ID 179849 (str. 1-8))Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasleLeto - 2012Jezik - angleškiCOBISS.SI-ID - 4419903
Avtor
Bevc, Sebastjan |
Hojs, Radovan |
Ekart, Robert, 1967- |
Završnik, Matej |
Gorenjak, Maksimiljan |
Puklavec, Ludvik, 1957-2020
Teme
Diabetes Mellitus, Type 2 |
Sladkorna bolezen, tip 2 |
Kidney Failure, Chronic |
Ledvična odpoved, kronična |
Cystatin C |
Cistatin C |
Glomerular Filtration Rate |
Glomerulna filtracija, hitrost |
Overweight |
Prekomerna telesna teža
Vnos na polico
Trajna povezava
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Faktor vpliva
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Bevc, Sebastjan | 27593 |
Hojs, Radovan | 15751 |
Ekart, Robert, 1967- | 23191 |
Završnik, Matej | 23769 |
Gorenjak, Maksimiljan | 07616 |
Puklavec, Ludvik, 1957-2020 | 90888 |
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