VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Protein-protein binding site prediction by local structural alignment
    Carl, Nejc ...
    Generalization of an earlier algorithm has led to the development of new localstructural alignment algorithms for prediction of protein-protein bindingsites. The algorithms use maximum cliques on ... protein graphs to define structurally similar protein regions. The search for structural neighbors in the new algorithms has been extended to all the proteins in the PDB and the query protein is compared to more than 60000 proteins or over 300000 single-chain structures. The resulting structural similarities are combined and used to predict the protein binding sites. This study shows that the location of protein binding sites can be predicted by comparing only local structural similarities irrespective of general protein folds.
    Vir: Journal of chemical information and modeling. - ISSN 1549-9596 (Vol. 50, issue 10, 2010, str. 1906-1913)
    Vrsta gradiva - članek, sestavni del
    Leto - 2010
    Jezik - angleški
    COBISS.SI-ID - 4491290

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