VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Are urinary bisphenol A levels in men related to semen quality and embryo development after medically assisted reproduction?
    Knez, Jure, dr. med., 1982- ...
    Objective: To evaluate whether urinary bisphenol A (BPA) levels in men adversely influence semen quality and embryo development after medically assisted reproduction. Design: Prospective, cohort ... study. Setting: University-based tertiary care center. Patient(s): A total of 149 couples undergoing their first or second IVF or intracytoplasmic sperm injection (ICSI) procedure. Intervention(s): None. Main Outcome Measure(s): Semen quality and embryo development parameters until the blastocyst stage after the IVF or ICSI procedure. Result(s): Bisphenol A was detected in 98% (n=146) of the samples with 0.1 ng/mL limit of detection. The geometric mean BPA concentration was 1.55 ng/mL. After the adjustment for potential confounders using linear regression models, an increase of natural logarithm transformed urinary BPA concentration was associated with lower natural logarithm transformed sperm count (ß=-0.241, 95% confidence interval [CI] -0.470 to -0.012), natural logarithm transformed sperm concentration (ß=-0.219, 95% CI -0.436 to 0.003), and sperm vitality (ß=-2.660, 95% CI -4.991 to -0.329). The embryo development parameters from oocyte fertilization to the blastocyst formation stage were not affected by BPA exposure. Conclusion(s): Urinary BPA concentrations in male partners of subfertile couples may influence semen quality parameters, but do not affect embryo development up to the blastocyst stage after medically assisted reproduction.
    Vir: Fertility and sterility. - ISSN 0015-0282 (Vol. 101, no. 1, Jan. 2014, str. 215-221)
    Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasle
    Leto - 2014
    Jezik - angleški
    COBISS.SI-ID - 4809023

    Povezava(-e):

    http://www.sciencedirect.com/science/article/pii/S0015028213031026#
    DOI

vir: Fertility and sterility. - ISSN 0015-0282 (Vol. 101, no. 1, Jan. 2014, str. 215-221)
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