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  • Diffusion layer caused by local ionic transmembrane fluxes
    Marhl, Marko ...
    Ionic concentrations in the close proximity of a carrier may be different than those in the bulk solution. An immediate layer in solution in which this situation occurs is known as a diffusion layer. ... The ratio between a flux rate of ions across the membrane and their diffusion rate in the solution determines a degree of this effect. It is of interest to study the interdependence between these two processes because it seems to represent a feedback system: the local concentrations are determined by the ionic fluxes, and the fluxes could be controlled by the local concentrations. Years ago diffusion layers were calculated using general diffusion equations and postulating a membrane to be homogeneous permeable in the plane. In contrast, the present mathematical model considers a single carrier as a transport system of ions across the membrane and electrodiffusion of these ions into the solutions from the site of the carrier. Ion fluxes are described by the Nernst-Planck equation for electrodifussion. The relation between the local electric potential and the ion concetrations is taken into account by the Poisson equation. The equations are solved numerically for radial spherical symmetry by the relaxation method. The model predicts concetration and potential profiles in dependence of the flux rate of particular ions. The predictions are evaluated with respect to the experimental data on ion fluxes of single carriers.
    Vir: International Meeting, Life Sciences 1995, 23-28 September 1995, Gozd Martuljek, Slovenia : abstracts and short papers (Vol. 431, supp. 2, no. 6, 1996, str. R259-R260)
    Vrsta gradiva - prispevek na konferenci
    Leto - 1996
    Jezik - angleški
    COBISS.SI-ID - 5299208

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