VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • The physiology of rodent beta-cells in pancreas slices
    Rupnik, Marjan
    Beta-cells in pancreatic islets form complex syncytia. Sufficient cell-to-cellelectrical coupling seems to ensure coordinated depolarization pattern and insulin release that can be further modulated ... by rich innervation. The complex structure and coordinated action dvelop after birth during fast proliferation of the endocrine tissue. These emergent properties can be lost due to various reasons later in life and can lead to glucose intolerance and diabetes mellitus. Pancreas slice is a novel method of choice to study the physiology of beta-cells still embedded in their normal cellulo-social context. I present major advantages, list drawbacks and providean overview on recent advances in our understanding of the physiology of beta-cells using the pancreas slice approach.
    Vir: Acta physiologica. - ISSN 1748-1708 (195, 2009, str. 123-138)
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - slovenski
    COBISS.SI-ID - 62051585

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