VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • Combined therapy of undifferentiated carcinoma of nasopharyngeal type
    Došen, Danijel ...
    From November 1989 to October 1993, 339 patients with stage IV undifferentiated carcinoma of nasopharyngeal type (UCNT) were enrolled in a randomized trial comparing neoadjuvant chemotherapy ... (cisplation, epirubicin, bleomycin - BEC) plus radiotherapy (171 patients) vs. radiotherapy alone (168 patients). All patient characteristics were well-balanced in both arms. The overall response rate assessed clinically by the investigator at the end of chemotherapy was 91% (WHO) with 47% CR and 4% PR. Three months after the completion of radiotherapy, a CR (clinical + CT scan) was observed in 55% of the combined treatment group compared to 34% in the radiotherapy-alone group (p<0.01). Tumor recurrence or progression was observed in 55/171 patients in the chemotherapy arm (32.7%), compared to 92/168 patients in the radiotherapy-alone arm (54.7%) (p<0.01). In conclusion, the addition of BEC type chemotherapy, has changed the proportion of UCNT patients continously disease free but the overall survival data are not yet mature.
    Vir: Radiology and oncology. - ISSN 1318-2099 (Let. 31, št. 2, 1997, str. 181-185)
    Vrsta gradiva - članek, sestavni del
    Leto - 1997
    Jezik - angleški
    COBISS.SI-ID - 7176921

    Povezava(-e):

    Digitalna knjižnica Slovenije - dLib.si

vir: Radiology and oncology. - ISSN 1318-2099 (Let. 31, št. 2, 1997, str. 181-185)
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