VSE knjižnice (vzajemna bibliografsko-kataložna baza podatkov COBIB.SI)
  • The distinct steps of cell detachment during development of mouse uroepithelial cells in the bladder
    Jezernik, Kristijan ; Sterle, Maksimiljan ; Batista, Urška
    In developing mouse urinary bladder the urothelial cells respond to urine accumulation by cell detachment, i.e. desquamation. To elucidate the steps of urothelial cell detachment during embryonic ... development and first urine accumulation in bladder lumen, superficial and intermediate cell layers were investigated. Different electron microscopic and cytochemical methods have been used. it was possible to distinguish between an early and late events on the basis of have been used. It was possible to distinguish between an early and late events on the basic of morphology. At the beginning cell detachment involves interruption of tight junctions between neighbouring superficial cells and the formation of numerous endocytotic vesicles. Endocytotic and cup-shaped vesicles then fuse and form large parallel rows of vacuoles and multivesicular bodies in desquamating superficial cells and in the neighbouring superficial and intermediate cells. These observations clearly demonstrate the existence of specific steps during the detachment of embryonicuroepithelial cells. Apoptosis accompanies cell desquamatin. Only predetermined superficial bridge cells die in apoptotic manner.
    Vir: Cell biology international. - ISSN 1065-6995 (Let. 21, št. 1, 1997, str. 1-6)
    Vrsta gradiva - članek, sestavni del
    Leto - 1997
    Jezik - angleški
    COBISS.SI-ID - 7504857

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