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  • Emergency care of patients receiving non-vitamin K antagonist oral antocoagulants
    Eikelboom, John W. ...
    Non-vitamin K antagonist oral anticoagulants (NOACs), which inhibit thrombin (dabigatran) and factor Xa (rivaroxaban, apixaban, edoxaban) have been introduced in several clinical indications. ... Although NOACs have a favourable benefit-risk profile and can be used without routine laboratory monitoring, they are associated - as any anticoagulant - with a risk of bleeding. In addition, treatment may need to be interrupted in patients who need surgery or other procedures. The objective of this article, developed by a multidisciplinary panel of experts in thrombosis and haemostasis, is to provide an update on the management of NOAC-treated patients who experience a bleeding episode or require an urgent procedure. Recent advances in the development of targeted reversal agents are expected to help streamline the management of NOAC-treated patients in whom rapid reversal of anticoagulation is required.
    Vir: British Journal of Anaesthesia. - ISSN 0007-0912 (Vol. 120, no. 4, 2018, str. 645-656)
    Vrsta gradiva - članek, sestavni del
    Leto - 2018
    Jezik - angleški
    COBISS.SI-ID - 863651
    DOI

vir: British Journal of Anaesthesia. - ISSN 0007-0912 (Vol. 120, no. 4, 2018, str. 645-656)
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