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  • Micronuclei in cytokinesis-blocked lymphocytes of patients following iodine-131 radiotherapy = Mikro jedra v limfocitih z zavrto citokinezo pri bolnikih po radioterapiji z I-131
    Kašuba, Vilena ; Kusić, Zvonko ; Garaj-Vrhovac, Vera
    The micronucleus assay in cytochalasin-B cytokinesis blocked peripheral blood lymphocytes in 10 patients with hyperthyreosis and various types of thyroidal carcinomas was investigated. Patients ... receivcd 259-5180 MBq I-131 sodium iodide perorally. Micronucleus (MN) frequencies were measured before and afterI-131 administration. Pre treatment MN results were regarded as controls.Our results show considerable variability concerning age and activityapplied. Also, the number of MN and the number of binucleated cells with micronuclei (BNMN) showed Poisson regression adjust for within subject correlation overdispersion. Log dose alone was not significant. The interaction of time and dose was significant at higher doses, while the rate of MN changing was slower. Relative risk time was calculated for the lowest dose (259 MBq). By doubling the dose, the rate of daily increase in the numberof MN and BNMN decreases by approximately 5% (Relative risk MN=0.955; Relative riskBNMN= 0.954).
    Vir: Radiology and oncology. - ISSN 1318-2099 (Letn. 33, št. 1, March 1999, str. 35-41)
    Vrsta gradiva - članek, sestavni del
    Leto - 1999
    Jezik - angleški
    COBISS.SI-ID - 9752025

    Povezava(-e):

    Digitalna knjižnica Slovenije - dLib.si

vir: Radiology and oncology. - ISSN 1318-2099 (Letn. 33, št. 1, March 1999, str. 35-41)
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