Fakulteta za farmacijo, Ljubljana (FFALJ)
  • Design, synthesis and structure-activity relationships of new phosphinate inhibitors of MurD
    Štrancar, Katja ; Blanot, Didier ; Gobec, Stanislav, 1970-
    A series of new phosphinate compounds were designed and synthesized as inhibitors of the D-glutamic acid-adding enzyme (MurD) involved in peptidoglycan biosynthesis. They were tested against the MurD ... enzyme from Escherichia coli, allowing initial structure-activity relationships to be deduced. Two compounds had IC50 values near 100 lM and constitute a promising starting point for further development
    Vir: Bioorganic & Medicinal Chemistry Letters. - ISSN 0960-894X (Vol. 16, no. 2, 2006, str. 343-348)
    Vrsta gradiva - članek, sestavni del
    Leto - 2005
    Jezik - angleški
    COBISS.SI-ID - 1836145

vir: Bioorganic & Medicinal Chemistry Letters. - ISSN 0960-894X (Vol. 16, no. 2, 2006, str. 343-348)

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