Fakulteta za farmacijo, Ljubljana (FFALJ)
  • Novel findings in drug-induced dendritic cell tolerogenicity
    Švajger, Urban ; Obermajer, Nataša ; Jeras, Matjaž
    Dendritic cells (DCs) constitute a unique set of antigen-presenting cells (APCs), equipped with the potential to initiate strong immune responses as well as to critically regulate immunity. ... Tolerogenic or "alternatively activated" DCs show remarkable properties in regulating immune responses both in vitro and in vivo. Furthermore, tolerogenic DCs are now beginning to be tested in clinical studies. Use of pharmacological agents to induce maturation-resistant tolerogenic DCs is a popular approach. In this review, wewill discuss already recognized, as well as recently discovered, potential pharmacological agents, their mechanism of action, and the way in which they induce tolerance in DCs.
    Vir: International reviews of immunology. - ISSN 0883-0185 (vol. 29, no. 6, 2010, str. 574-607)
    Vrsta gradiva - članek, sestavni del
    Leto - 2010
    Jezik - angleški
    COBISS.SI-ID - 2904945

vir: International reviews of immunology. - ISSN 0883-0185 (vol. 29, no. 6, 2010, str. 574-607)

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