Univerzitetni rehabilitacijski inštitut RS, Ljubljana (IRLJ)
  • Heart-rate reduction with adjusted-dose ivabradine in patients undergoing coronary computed tomographic angiography : a randomized trial
    Kacijan, Blaž ...
    Our prospective, randomized, open-label study assessed the efficacy of a heart rate-lowering, adjusted-dose protocol with ivabradine prior to coronary computed tomographic angiography (CCTA). ... Patients undergoing CCTA were randomized to 7 days of adjusted-dose ivabradine or standard care (ie, no additional medication). Heart rate and ß-blocker and antianxiety medication use on the day of the CCTA were recorded. One hundred one patients were randomized (mean age, 60 [SD, 13] years; 66% women). Significantly more patients on ivabradine had heart rates of 60 beats per minute or less at the time of the CCTA scan (48% vs 8%, P < 0.01); accordingly, fewer patients on ivabradine needed additional heart rate lowering with ß-blockers (40% vs 86%, P < 0.01), as well as antianxiety medication (18% vs 39%, P < 0.05), and also required lower doses of intravenous ß-blockers (4 [SD, 2] vs 7 [SD, 5] mg, P < 0.05). A 7-day premedication protocol with ivabradine effectively lowers heart rate in patients undergoing CCTA.
    Vir: Journal of computer assisted tomography. - ISSN 0363-8715 (Vol. 41, no. 3, 2017, str. 360-363)
    Vrsta gradiva - članek, sestavni del
    Leto - 2017
    Jezik - angleški
    COBISS.SI-ID - 2295657

    Povezava(-e):

    https://doi.org/10.1097/RCT.0000000000000556
    DOI

vir: Journal of computer assisted tomography. - ISSN 0363-8715 (Vol. 41, no. 3, 2017, str. 360-363)

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