Nacionalni inštitut za biologijo (NIB)
  • Stress knowledge map; Elekt... (naslovnica)
    Stress knowledge map [Elektronski vir] : a knowledge graph resource for systems biology analysis of plant stress responses
    Bleker, Carissa ...
    Stress Knowledge Map (SKM; https://skm.nib.si) is a publicly available resource containing two complementary knowledge graphs that describe the current knowledge of biochemical, signaling, and ... regulatory molecular interactions in plants: a highly curated model of plant stress signaling (PSS; 543 reactions) and a large comprehensive knowledge network (488 390 interactions). Both were constructed by domain experts through systematic curation of diverse literature and database resources. SKM provides a single entry point for investigations of plant stress response and related growth trade-offs, as well as interactive explorations of current knowledge. PSS is also formulated as a qualitative and quantitative model for systems biology and thus represents a starting point for a plant digital twin. Here, we describe the features of SKM and show, through two case studies, how it can be used for complex analyses, including systematic hypothesis generation and design of validation experiments, or to gain new insights into experimental observations in plant biology.
    Vir: Plant communications [Elektronski vir]. - ISSN 2590-3462 (Vol. 5, iss. 6, [art. no.] 100920, 10 Jun. 2024, str. 1-15)
    Vrsta gradiva - e-članek
    Leto - 2024
    Jezik - angleški
    COBISS.SI-ID - 198383363

    Povezava(-e):

    https://doi.org/10.1016/j.xplc.2024.100920
    https://skm.nib.si
    DiRROS - Digitalni repozitorij raziskovalnih organizacij Slovenije
    DOI

Digitalne vsebine: dCOBISS

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