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  • Poti razgradnje celičnih sestavin = Degradation pathways of cell ingredients
    Veranič, Peter ; Pšeničnik, Majda
    The degradation of cell ingredients takes place mainly in lysosomes. The most important and also the best known degradation pathway is autophagy, where a sequestrating membrane separates a part of ... the cytoplasm so forming an autophagic vacuole. Degradation of the autophagic vacuole ingredients starts after the fusion of the autophagic vacuole with a lysosome. Some cytosolic proteins are introduced to a lysosome by a heat-shock protein (Hsp 70) in a process called carrier mediated proteolysis. Another pathway of lysosomal protein degradation is crinophagy where the secretory vesides containing newlysynthesised proteins fuse with the lysosomal membrane instead of fusing with the plasma membrane. Part of the proteolysis is localised in the cytosol and is known as nonlysosomal proteolysis. In this degradation, large protein complexes proteasomes and protein ubiquitin are involved. The degradation products are reused for the synthesis of new cell components. Thus degradationprocesses are involved in recycling of the cell ingredients.
    Vir: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 38, [št.] 1, mar. 1999, str. 83-90)
    Vrsta gradiva - članek, sestavni del
    Leto - 1999
    Jezik - slovenski
    COBISS.SI-ID - 10159833

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    Digitalna knjižnica Slovenije - dLib.si

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