Narodna in univerzitetna knjižnica, Ljubljana (NUK)
Naročanje gradiva za izposojo na dom
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi
  • Neinvazivno spremljanje zavrnitvene reakcije z analizo intramiokardnih elektrogramov pri bolniih po ortotopni presaditvi srca. Naše izkušnje s prvimi sedmimi bolniki = Intramyocardial electrograms for noninvasive monitoring of rejection in cardiac transplant recipients. Initial experience with seven cases
    Zupan, Igor, 1961- ; Gorkič, Nataša ; Zorman, Darko
    Background. Despite the use of increasingly specific immunosuppressive therapy, rejection remains the leading cause of death in cardiac transplant patients. Clinical manifestations tend to occuratan ... advanced stage of the disease when its course is difficult to reverse. Endomyocardial biopsy is the gold standard for early detection and monitoring of cardiac transplant rejection. However, this approach is invasive and not suitable for routine use. A new, noninvasive alternative for monitoring cardiac transplant patientsuses analysis of the ventricular evoked response (EPP) obtained by programmed electrical stimulation. Rejection-sensitive parameters (RSP) and infection-specific parameters (ISP) are extracted from changes in the slope ofthe T-wave and from the duration of repolarization, respectively. Rejection grade 2 or higher is diagnosed without exposing the patient to undue risk. Theresults obtained accord with biopsy findings. Methods. During the heart transplant procedure, two epimyocardial electrode leads are placed on the right ventricular outflow tract and the left ventricular lateral wall, and connected to the Physios CT'M 01 pacemaker (Biotronik, Germany) implanted in the subcutaneous tissue of the abdominal wall For the anglysis of intramyocardial electrograms separate left ventricular and right ventricular pacing at a rate of 100 beats/ min and lasting 60 seconds is required, following the same protocol. The electrogram data are then transferred via theInternet to the central data processing site in Graz (Austria). The processed data in the form of prognostic curves are sent back within a few minutes. (Abstract truncated at 2000 characters)
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 70, št. 6, jun. 2001, str. 335-339)
    Vrsta gradiva - članek, sestavni del
    Leto - 2001
    Jezik - slovenski
    COBISS.SI-ID - 13588185

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    Digitalna knjižnica Slovenije - dLib.si

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