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  • Ocena vala P300 pri bolnikih s Parkinsonovo boleznijo = P300 wave confirmation in patients with Parkinson's disease
    Pišljar, Marko ; Denišlič, Miro ; Meh, Duška
    Background. Mild to moderate cognitive dysfunction is a frequent complaint of patients with Parkinson's disease, though the clinical picture of dementia is rarely reported. Methods. The development ... of cognitive deficits seams to be associated with hypokinesia and rigidy rather than tremor. In our study, auditory ERP were used to confirm cognitive alterations in two groups of non-dementedpatients with idiopathic Parkinson's disease. Mini mental test wasperformed to exclude clinical picture of dementia. Patients were classifiedaccording to the Hoehen-Yahr and Webster scale. The Beck depression score in Parkinson's patient was assessed. Auditory event related potentials were recorded using the "oddball" paradigm. The waves N100, P200, N200 and P300 were recorded and their latencies and amplitudes measured Results and conclusions. The P300 latencies in both patients group were significantly longer (p < 0.05), than in the control group. P300 latency was longer in non tremor group. There were no significant statistical differences in latencies between the both groups. All patients had normal N100 latency. Significant decline of P300 amplitude was found only in non-tremor group (p < 0.001).
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 70, št. 11, 2001, str. 647-650)
    Vrsta gradiva - članek, sestavni del
    Leto - 2001
    Jezik - slovenski
    COBISS.SI-ID - 14271449

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    Digitalna knjižnica Slovenije - dLib.si

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