Narodna in univerzitetna knjižnica, Ljubljana (NUK)
Naročanje gradiva za izposojo na dom
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi
  • Pomen topnega receptorja za interlevkin-2 pri sepsi = Significance of soluble interleukin-2 receptor in sepsis
    Pokrajac, Tatjana ...
    Background. The soluble interleukin-2 receptor (s-IL-2R) is a soluble cytokinereceptor which directly reflects the levels of the IL-2 receptor on lymphocytes T, which, along with the IL-2 itself, is ... important for the specific immune response. The aim of the study. We attempted to prove diagnostic and prognostic significance of s-IL-2R in sepsis cases. Patients and methods. In the period of three years we examined 64 healthy blood donors and subjects in systematic health examinations and examined 50 septic patientswith clinical and laboratory symptoms of sepsis treated in units for the intensive therapy of adults at the Clinic for Infectious Diseases and Febrile States at the Clinic Centre of Ljubljana. The assay for s-IL-2R was performed with a kit from Eurogenetic (Belgium). Results. We proved that the median concentration of s-IL-2R in septic patients with positive and negative blood culture are significantly higher than healthy subjects (p<0.05) and werealso significantly higher in the blood of dead patients than in the blood of survivors (p<0.05). The mean concentration of s-IL-2R did not differ in septic patients with positive blood culture from those with negative blood culture and did not differ for gram negative pathogenes from those for gram positive pathogens. Time dynamics showed the increase levels of s-IL-2R for the first 48 hours. Conclusions. s-IL-2R levels are elevated in adults with sepsis. Elevation of s-IL-2R are significantly associated with death.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 70, št. 12, dec. 2001, str. 737-740)
    Vrsta gradiva - članek, sestavni del
    Leto - 2001
    Jezik - slovenski
    COBISS.SI-ID - 14318553

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    Digitalna knjižnica Slovenije - dLib.si

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