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  • Zdravljenje malignega melanoma žilnice z brahiterapijo (Ru-106) - 14-letne izkušnje = Brachytherapy (Ru-106) for choroidal melanoma - our experience of 14 years
    Novak-Andrejčič, Katrina ...
    Background. For many years, malignant melanoma of the choroid was treated withprompt enucleation. Recently several eye preserving methods have been developed. The aim of our study was to report on ... the therapeutic results in patients with primary choroidal melanoma treated with ruthenium-106 brachytherapy. Methods. A retrospective chart review of 65 patients treated with ruthenium-106 brachytherapy for choroidal melanoma from 1986 to 1997 was performed. The patients were 22 to 78 years old (mean 54.5 years). The height of the tumors was within the range of 1.5 to 7.1 mm (mean 4.7mm). The mean dose to the apex of the tumor was 100 Gy. Mean follow-up period was 90.6 months (range 22 to 169 months). Fundus photography, diagnostic ultrasound andbest corrected visual acuity were performed during each examination before and after radiation. Results.12 (18.4%) patients died from metastatic spread and 2 from other causes. Complete tumor regression occurred in 12 (18.4%) patients. Tumor regression was partial in 31 (47.7%) patients. Enucleation because of tumor growth was performed in 11(16.9%) patients and in 2 for otherreasons. 19 (30%) eyes retained visual acuity better than 0.5 and 49% of patients had visual acuity better than 0.1. Conclusions. Ruthenium brachytherapy has proved to be an effective conservative treatment for uveal melanomas thinner than 7mm. The present results correspond well with data in the literature. Visual outcome correlates with tumor location.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 71, supl. 2, apr. 2002, str. II-67-II-70)
    Vrsta gradiva - članek, sestavni del
    Leto - 2002
    Jezik - slovenski
    COBISS.SI-ID - 14711769

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    Digitalna knjižnica Slovenije - dLib.si

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