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  • Slikovna elektroretinografija v primerjavi s kinetično in statično perimetrijo in vidno ostrino pri pigmentni retinopatiji = Pattern electroretinography in relation to kinetic and static perimetry and visual acuity in retinitis pigmentosa
    Popović, Petra, 1969- ...
    Background. This study was conducted to assess whether pattern ERG is a sensitive test in evaluating the retinal function in patients with retinitis pigmentosa. We wanted to determine how pattern ... ERG, reflecting the activity ofinner retinal layers, is related to other psychophysical tests such as perimetry and visual acuity. Methods. An analysis was performed on 50 eyes of 25 patients with typical rod: one retinitis pigmentosa. The standard Snellen visual acuity was tested. Visual field sensitivity was measured with automatedstatic perimetry (Octopus G2 program) where mean defect was taken as an index of visual field loss. In kinetic perimetry (Goldmann).the average radius of the visual field measured with target 11/4 and V/4 was calculated. Transient pattern ERG and all five flash ERG responses were also measured according to ISCEV standards. Amplitudes of pattern ERG P50 and N95 waves werecompared to results of visual acuity and visual field testing. Results. Inour group of 25 RP patients with visual acuity ranging from 0.16 to 1.0, PERG responses were preserved much better than full field ERGs. 72% of them had still recordable PERG responses, while 48% had cone and only 32% maximal responses. Scotopic rod responses were extinguished in all eyes. The normalized amplitudes of the PERG responses were also much higher (43.5%) thancone (22.5%) or maximal responses (4.5%). A strong correlation of both P50and N95 amplitudes with Octopus mean defect index was found. In kinetic perimetry the correlation with PERG amplitudes was also high, but it was better with II/4 than with V/4 target. Patients with high preserved ERG responses had good visual acuity. In all patients with visual acuity less than0.4 both flash and pattern ERG responses were already absent. (Abstract truncated at 2000 characters).
    Vrsta gradiva - prispevek na konferenci
    Leto - 2002
    Jezik - slovenski
    COBISS.SI-ID - 14714841