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  • Sindrom dolgega intervala QT = Long QT syndrome
    Dolinšek, Jernej, 1970- ...
    Long QT syndrome (LQTS) is caused by abnormal electrophysiology of the heart, manifesting with typical ECG changes and life - threatening arrhythmias. Two hypotheses are trying to explain the ... pathogenesis of the LQTS: sympathetic imbalance and intracardiac abnormality hypothesis. Diagnosis of LQTS is based upon diagnostic criteria including clinical findings, family history and ECG changes. A point system enables us to separate patients into three categories with respect to the probability of the disease. Of particular importance are patients having acquired prolongation of QT interval mainly caused by administration of certain medications or electrolyte imbalance in predisposed patients. Beta-blockers are essential therapy for patients with LQTS. Therapy may also include implantation of cardiac pacemaker or cardioverter - defibrilator, and in rare patients left cardiac sympathetic denervation. Newermedications, acting on ion channels, represent a promising tool for the management of LQTS patients in the future.
    Vrsta gradiva - članek, sestavni del
    Leto - 2002
    Jezik - slovenski
    COBISS.SI-ID - 15097305