Narodna in univerzitetna knjižnica, Ljubljana (NUK)
Naročanje gradiva za izposojo na dom
Naročanje gradiva za izposojo v čitalnice
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Urnik dostave gradiva z oznako DS v signaturi
  • Uspešnost profilaktičnih ukrepov proti hepatitisu B pri novorojencih HBsAg pozitivnih mater v obdobju 1997-2002 na Celjskem = The effectiveness of prophylactic measures against hepatitis B in newborns of HBsAg positive mothers for the period 1997-2002 in Celje region
    Lešničar, Gorazd ...
    Background. There are about 400 million hepatitis B carriers in the world, of these some 20, 000 live in Slovenia. Due to the low prevalence of chronic hepatitis B carriers in our country, the ... infection is most requently transmitted by means of sexual intercourse with an infected person, or parenterally, by blood. Perinatal transmissions from an infected mother to herchild which represent the most frequent infection route in the hyperendemicregions of Asia and Africa, should not be ignored either. Methods.A retrospective study was carried out at the Department for InfectiousDiseases and Febrile Conditions of the General Hospital Celje with the aim to assess the success of postnatal and later prophylaxis of children against hepatitis B infection for the period 1997-2002. Children aged 1-5 years were examined using clinical biochemical and virological tests for hepatitis B, hepatitis C and HIV. Results. We examined 23 out of 33 invited HBsAg positive mothers and their children, who received immediate postnatal prophylaxis with specific immunoglobulins and vaccination against hepatitis B.After wards they received two additional vaccinations in a Pediatric Clinic or in an Institute of public health Celje. At the time of follow-up examination none of the children had positive serum markers for active viral infection with hepatitis B, hepatitis C and HIV. All the children had sufficiently high titers of protective antibodies against hepatitis B virus present in the serum (> 10 IU/ml). AgHBs became negative in one mother only while the rest remained asymptomatic carriers of hepatitis B virus. Consequently no treatment was required. Conclusions. Regardless of the out standingly favorable results of postnatal prophylaxis against hepatitis B in our study subjects, the small number of children receiving this protection a nd the short follow-up period do not allow any long-term prognoses. (Abstract truncated at 2000 characters).
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 71, št. 11, nov. 2002, str. 685-689)
    Vrsta gradiva - članek, sestavni del
    Leto - 2002
    Jezik - slovenski
    COBISS.SI-ID - 15743961

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