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Primerjava dveh ureaznih bioptičnih testov za dokaz okužbe s Helicobacter pylori pred antimikrobnim zdravljenjem in po njem = Prospective comparison of two rapid urease tests for the diagnosis of Helicobacter pylori before and after antimicrobial treatmentTepeš, BojanBackground. Rapid urease bioptic test (RUT) is a basic test for detection of Helicobacter pylori at upper gastrointestinal endoscopies. There are differentRUT tests available commercially and the ... main difference between themlies in their reaction time. In every day clinical practice it is important for the physician to prescribe treatment at the time of upper gastrointestinal endoscopy. Methods. This study presents comparison of two different RUTs (Pliva bioptat(e) and CLO) in terms of their accuracy and needed reaction time for the test to become positive. Fifty duodenal ulcer patients with Helicobacter pylori infection were included. All of them were tested with two rapid urease tests, histology, culture and 13C urea breath test. Results. Sensitivity and specificity of both RUTs were very high and without any difference between them. Statistically significant difference appeared in the form of time needed for the test to become positive. Pliva bioptat(e) test became positive after 30 minutes in 48/50 (96%) of patients before introduction of the antimicrobial treatment compared with 32/50 (64%) of patients tested with the CLO test (p < 0.05). A month after antimicrobial therapy Pliva bioptat(e) test was positive in 9/11 (81%) after 30 minutes, compared with 3/11 (27%) of patients with the CLO test (p < 0.05). Conclusions. Pliva bioptate test has practical advantages for physicians (endoscopists) who need a rapid and accurate method of diagnosing of Helicobacter pylori infection before and after antimicrobial therapy.Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 72, št. 9, sep. 2003, str. 503-505)Vrsta gradiva - članek, sestavni delLeto - 2003Jezik - slovenskiCOBISS.SI-ID - 16995801
Avtor
Tepeš, Bojan
Teme
Stomach Ulcer |
Diagnosis |
Pathology |
Helicobacter Pylori |
Isolation And Purification |
Urease |
Diagnostic Use |
Sensitivity And Specificity |
Helicobacter pylori |
Ureaza |
Želodčni ulkus |
Občutljivost in specifičnost |
ulkus |
diagnostika |
helicobacter pylori |
zdravljenje
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vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 72, št. 9, sep. 2003, str. 503-505)
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Tepeš, Bojan | 07942 |
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