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  • Primerjava endotelijske funkcije in magnetoresonančnih lastnosti žilne stene med bolniki s klasično in dilatativno obliko ateroskleroze = Comparison of endothelial function and magnetic resonance characteristics of vessel wall among patients with classic and dilatative atherosclerosis
    Štalc, Jurij ; Tominc, Uroš
    Background: Dilatative atherosclerosis is a rare form of degenerative process manifested by arterial aneurysms. It is believed that endothelial dysfunction is involved in dilatative atherosclerosis. ... For estimation of systemic endothelial dysfunction a standardized endothelium-dependent vasodilatation test can be used. Alteration of arterial wall in aneurysm can be visualized and estimated by high-resolution magnetic resonance imaging (MRI). Aim: The aim of our study was to compare endothelial function and some MRI structural and morphological characteristics of dilatative atherosclerosis. Hypotheses: 1. Endothelial function differs among groups. 2. MR signal from the vessel wall of popliteal aneurysm differs from that of atherosclerotic vessel wall. 3. MR signal from the vessel wall of popliteal aneurysm differs in comparison to the signal from nearby non-dilated site. 4. Thickness of the vessel wall atthe dilated (aneurysmal) site equals to the thickness of non-dilated site ofthe same vessel. Methods: We included 12 male patients with popliteal arteryaneurysm (group A) and 9 male patients with classic atherosclerosis (group K). Endothelial function was estimated by endothelium-dependent vasodilatation test. In all patients a high-resolution cross-section MRI through two standardized locations was made. The distal location was knee-joint fissure in group K or the widest section of the aneurysm in the group A. The proximal location was at least 6 cm proximally to the distal one in the group K or a non-dilated section of artery in the group A. The data taken from MR images (average intensity of the signal, standard deviation of the signal and geometrical characteristics of the vessel wall) was then statistically compared. Results: The comparisons of endothelium-dependent and endothelium-independent dilatation between groups showed no significant difference. (Abstract truncated at 2000 characters).
    Vir: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 42, št. 3, sep. 2003, str. 229-242)
    Vrsta gradiva - članek, sestavni del
    Leto - 2003
    Jezik - slovenski
    COBISS.SI-ID - 17452505

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    Digitalna knjižnica Slovenije - dLib.si

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