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  • Sindrom Melkersson-Rosenthal = Melkersson-Rosenthal syndrome
    Balkovec, Valerija ; Gabrič Zirkelbach, Maja
    Background. Granulomatous cheilitis is a rare chronic swelling of the lip due to granulomatous inflammation. Miescher cheilitis is the term used when the granulomatous changes are confined to the ... lip. Miescher cheilitis is generallyregarded as a monosymptomatic form of the Melkersson-Rosenthal syndrome (SMR). SMR is characterized by a triad, including orofacial swelling facial palsy and lingua plicata. Aetiology of disease is unknown. Virus infection, several other infectious conditions, allergic reactions and Crohn'sdisease may be involved in the aetiology of SMR. Patients and methods. This paper describes a case of 59 year old male patient with grartulomatous cheilitis. Because of swelling of the lip and the cheek allergic patch and prick tests were performed. All tests were negative. Skin biopsy of the affected tissue showed granulomas inflammatory cell infiltration in the dermis. Other systemic granulomatous diseases such a sarcoidosis and tuberculosis were excluded. Results. A systemic therapy with sulphonyldianilyne 50 mg daily was started. After one year a swelling is less visible. Conclusions. SMR needs to be recognized by the clinician with persistent swelling of the lip, chin and cheeks.Their duration is short at first, subsiding completely in a few hours or days, and thus simulating angio-oedema. After recurrent attacks at irregular intervals, the oedema becomes persistent. Pull confirmation of the diagnosis of SMR requires a histological examination.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 73, št. 12, dec. 2004, str. 907-909)
    Vrsta gradiva - članek, sestavni del
    Leto - 2004
    Jezik - slovenski
    COBISS.SI-ID - 19101913

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    Digitalna knjižnica Slovenije - dLib.si

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