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  • Analiza živčnožilne sklopitve z vidnimi evociranimi potenciali in doplersko sonografijo = The analysis of neurovascular coupling by visual evoked potentials and Doppler sonography
    Zaletel, Marjan, 1963-
    The term neurovascular coupling denotes the relationship between neuronal activity and regional cerebral blood flow. A method that would enable analysisof neurovascular coupling in humans is still to ... be discovered. The aimof our study was to establish whether it is possible to analyze neurovascular coupling noninvasively by simultaneously measuring visual evokedpotentials (VEP) and visually evoked cerebral blood flow responses (VEFR) by transcranial Doppler (TCD). The records were made from 30 healthy volunteers of both sexes aged 38.0 +- 9.6 years. The mean arterial velocity inthe left middle cerebral artery (vmMCA) and the mean arterial velocity in the right posterior cerebral artery (vmPCA) were monitored by using TCD. The VEPs were recorded from occipital leads. Neuronal activity was changed by changing visual contrast. The relationship between VEP and VEFR was tested using linear regression analysis. The VEFRs at 100% visual contrast were higher than those at 10% visual contrast (p < 0.01) and the VEFRs at 10% visual contrast higher than those at 1% visual contrast (p < 0.01). In addition, the VEPs at 100% visual contrast were higher than those at 10% visual contrast (p < 0.01) and the VEPs at 10% visual contrast higher than those at 1% visual contrast (p < 0.01). The relationship between the VEPs in the VEFR was moderate and significant (r = 0.66; p < 0.01). It was concluded that simultaneous measuring of VEPs and VEFRs enable us to analyze neurovascular coupling in healthy subjects.
    Vir: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 43, št. 4, dec. 2004, str. 363-372)
    Vrsta gradiva - članek, sestavni del
    Leto - 2004
    Jezik - slovenski
    COBISS.SI-ID - 19161305

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    Digitalna knjižnica Slovenije - dLib.si

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