-
Živčni rastni dejavnik - njegova vloga pri astmi in alergijskih reakcijah = Nerve growth factor - its role in asthma and allergic reactionsŠtempelj, Mateja ; Ferjan, IlonkaBackground. Nerve growth factor (NGF) plays an important role in the growth, differentiation and survival of peripheral and central neurons. Beside neurotrophical activity, NGF exerts several effects ... on the cells of immune system. Recent studies have demonstrated the importance of NGF in asthma and allergic diseases, such as allergic rhinitis and urticaria. Conclusions. Elevated NGF concentractions have been observed in biological fluids of patients with asthma and allergic diseases. The concentraction of NGF further rises after sensitization with allergen. Numerous studies have reported NGF synthesis by almost all inflammatory cells. In addition, most inflammatory cells express TrkA and p75 NGF receptors. Since the activation of mast cells with NGF evokes release of histamine within minutes, this could indicate the potential role of NGF in the early stage of allergic reaction. The late phase of allergic reaction is characterized by infiltration of eosinophils. The activation of eosinophils with NGF evokes release of cytotoxic mediators (major basic protein). Several data also suggest that NGF plays a role in airway inflammation, bronchoconstriction, hyperresponsiveness and remodelling,all observed in patients with asthma. All these results indicate that NGF contributes to responses in allergic inflammation and asthma.Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 74, št. 5, maj 2005, str. 307-309)Vrsta gradiva - članek, sestavni delLeto - 2005Jezik - slovenskiCOBISS.SI-ID - 19280857
Avtor
Štempelj, Mateja |
Ferjan, Ilonka
Teme
Asthma |
Nerve Growth Factors |
Receptors, Nerve Growth Factor |
Hypersensitivity |
Mast Cells |
Inflammation |
Histamine |
Astma |
Preobčutljivost |
Receptorji, živčni, rastni faktor |
Tkivni bazofilci |
Živec, rastni faktorji |
Histamin |
Vnetje |
živčevje |
živčni rastni faktor |
fiziologija |
infekcije |
astma |
alergija
vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 74, št. 5, maj 2005, str. 307-309)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|---|
Štempelj, Mateja | 21386 |
Ferjan, Ilonka | 08313 |
Izberite prevzemno mesto:
Prevzem gradiva po pošti
Obvestilo
Gesla v Splošnem geslovniku COBISS
Izbira mesta prevzema
Mesto prevzema | Status gradiva | Rezervacija |
---|
Prosimo, počakajte trenutek.
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi