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  • Multiple primary malignancies in patients with lung cancer
    Kurishima, Koichi ...
    Background. To evaluate the incidence of multiple prirnary malignancies in lung cancer patient`s, we summarized our experience in lung cancer patients with multiple primary malignancies. Methods. A ... total of 1194 consecutive Lung cancer patients, who were admitted to our division over a 29 year period up toAugust 2004, were retrospectively analyzed. Results. Ninety-eight (8.2`) of 1194 lung cancer patients had multipte prirnary malignancies. Metachronous malignant disease comprised 77.6% and synchronous 21.4%. Multiple primary tumours in our patients were detected rnore frequent in the advanced stage of lung cancer (IIIA-IV 67.3%) than in the early stage (IA-IIB 32.7%). The histological examination of lung cancer revealed a preponderance of squamous cell carcinoma (40 patients, 40.8%). First primary tumours developed most commonly in gastrointestinal tract, fallowed by lung and uterus. Fifty-seven (85.1%) of 67 patients with aerogastrointestinal and head and neck cancers hada smoking habit. In 98 patients with multiple primary cancers, forty (40.8%) patients had stage IA-IIIA lung cancer, however, 26 (26.5%) had a surgical resection. Conclusions. Existing metachronous primary tumours proved to be a worse prognostic factor in non-small cell lung cancer patients (p=0.0480), while synchronous primary turnours were not, as well as there was not proven that multiple primary tumours were worse prognostic factors in patients with small cell lung cancer.
    Vir: Radiology and oncology. - ISSN 1318-2099 (Vol. 39, no. 1, mar. 2005, str. 49-53)
    Vrsta gradiva - članek, sestavni del
    Leto - 2005
    Jezik - angleški
    COBISS.SI-ID - 19321305

    Povezava(-e):

    Digitalna knjižnica Slovenije - dLib.si

vir: Radiology and oncology. - ISSN 1318-2099 (Vol. 39, no. 1, mar. 2005, str. 49-53)

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