Narodna in univerzitetna knjižnica, Ljubljana (NUK)
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Epidemiološke in klinične značilnosti Behçetove bolezni v Sloveniji = Epidemiological and clinical features of Behçet disease in SloveniaKraut, AleksandraBehcet disease (BD) is a chronic multisystemic inflammatory disease of unknowncause. Most prominent features are muco-cutaneous and ocular leasons with frequent profound visual loss. The aim is to ... report the presence of BD with ocular involvement in patients in Slovenia. Methods. A retrospective analysis of charts and outpatients records of patients with BD treated at University Eye Clinic of Ljubljana between January 1984 and Decembre 2004. International diagnostic criteria for the disease were considered. Main outcome measures were: sex, age at onset of uveitis, ocular features and complications, incidence of HLA B5 or 51, systemic treatment, complications oftreatment, and final visual acuity. Results. In the observational period 25 patients with ocular BD were treated. 16 patients were male, 9 were female. Onset of uveitis ranged between 16-47 years, mean at 34.2 years. All patients had recurrent bilateral panuveitis or retinal vasculitis. 15 patients were HLAB5 or 51 positive, 5 were negative and 5 were not tested. Beside local therapy all patients were on systemic therapy: Corticosteroids 25 patients, Azathioprine 13, Cyclosporine A 11, Cvclophosphamide 6, Chlorambucil 1, and Colhicine 1 patient. Final visual acuity was: light perception negative in twoeyes, < 0.2 in 13 eyes, from 0.2 to 0.6 in 12 eyes, and > 0.6 in 23 eyes. Conclusions. BD with ocular involvement is a rare disease in Slovenia. In spite of classic irnmunosuppressive therapy, in 15 eyes (30%) profound visual loss was observed. To maintain visual acuity an recognition of ocular involvement and appropriate treatment is important, as therapy is becoming more effective and determined.Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 74, št. 10, okt. 2005, str. 573-577)Vrsta gradiva - članek, sestavni delLeto - 2005Jezik - slovenskiCOBISS.SI-ID - 20413401
Avtor
Kraut, Aleksandra
Teme
Behcet's Syndrome |
Diagnosis |
Therapy |
Behcetov sindrom |
Behcetov sindrom |
sistemske bolezni |
očesne bolezni |
mrežnica |
epidemiologija
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vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 74, št. 10, okt. 2005, str. 573-577)
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Kraut, Aleksandra | 09155 |
Vir: Osebne bibliografije
in: SICRIS
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