Algoritmi zdravljenja raka dojke in novosti na tem področju = Treatment algorithms for breast cancer and new approaches
Čufer, Tanja, 1955- ; Snoj Šarvari, Nataša, 1973-
The treatment of breast cancer is multidisciplinary and encompasses both localand systemic therapy. Various types of breast cancer can be distinguished: operable breast cancer, locally advanced ...breast cancer and metastatic breast cancer. Systemic treatment of breast cancer, which includes cytostatic, hormonal and biological therapy, significantly improves chances for cure and breast conserving surgery in operable and locally advanced breastcancer, as well as for prolonged survival with modest quality of life inmetastatic disease. Adjuvant chemotherapy and adjuvant hormonal therapy withtamoxifen were found to improve survival rates of early breast cancer patients by more than a half and today over two thirds of patients are alreadycured. Evidence exists that the incorporation of new drugs, such as taxanes and aromatase inhibitors, will further improve the efficacy of breast cancer treatment. In addition, there are new biological drugs under development and due to already proven high efficacy of trastuzumab, it is expected that biologics will further improve cure rates of breast cancer patients. At this stage, we are moving from the era of empirical oncology to the era of molecular oncology, in which efficient treatments will be based on specific biological characteristics of each individual tumor.
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