Narodna in univerzitetna knjižnica, Ljubljana (NUK)
Naročanje gradiva za izposojo na dom
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi
  • Diagnostic performance of NT-proBNP in patients referred for specialized evaluation of heart failure signs and symptoms = Diagnostična uporabnost NT-proBNP pri bolnikih, ki so jih zaradi simptomov in znakov srčnega popuščanja napotili na specialistično obravnavo
    Jug, Borut, 1975- ...
    Amino-terminal pro-B-type natriuretic peptide (NT-proBNP) is an important diagnostic and prognostic marker of heart failure, however its diagnostic performance is affected by specifics of the ... screened population. Therefore, wesought to establish the diagnostic performance of NT-proBNP in patients referred for specialist evaluation due to signs and symptoms of heart failure.Consecutive outpatients (n=306) referred for evaluation of suspected heart failure to a university hospital heart failure clinic underwent clinicaland echocardiographic assessment, and had their NT-proBNP levels determined (using sandwich chemiluminescent immunoassay with two antibodies onan Elecsys analyser). Median NT-proBNP levels were significantly higher in patients with evidence of structural heart disease - 250 (interquartile range 7-282) pg/ml vs. 1671 (621-9120) pg/ml; a cut-off of 200 pg/ml discriminated them from individuals with no structural heart disease, with a 91% sensitivityand a 60% specificity. Apart from the severity of heart failure, the following other (statistically non-significant) determinants of NT-proBNP levels also emerged: age, gender and renal function. NT-proBNP is an accurate diagnostic marker in patients referred for specialized evaluation of heart failure signs and symptoms. However, when interpreting test results one shouldbe aware that several factors apart from heart failure severity influence NT-proBNP levels.
    Vrsta gradiva - članek, sestavni del
    Leto - 2006
    Jezik - angleški
    COBISS.SI-ID - 21962969