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  • The neuronal cell cycle as a mechanism of pathogenesis in Alzheimer's disease = Nevronski celični ciklus kot patogenetski dejavnik pri Alzheimerjevi bolezni
    Currais, Antonio ...
    Differentiated neurons display specific biochemical, physiological and morphological properties that apparently prevent them from further cell division. Nevertheless, expression of cell cycle ... modulators persists after neuronal differentiation and is upregulated under stress conditions, such as trophic factor deprivation, oxidative stress and the presence of DNA damaging agents. This apparent reactivation of the cell cycle has been postulated as a sine qua non for neuronal death in response to those stress conditions, particularly in Alzheimer's disease. However, the physiological and pathogenicimplications of a putative neuronal cell cycle are far from clear. Here, we discuss the notion of the neuronal cell cycle as a mediator of cell death in Alzheimer's disease.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 77, supl. II, 2008, str. II-13-II-20)
    Vrsta gradiva - članek, sestavni del
    Leto - 2008
    Jezik - angleški
    COBISS.SI-ID - 24288217

    Povezava(-e):

    Digitalna knjižnica Slovenije - dLib.si

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