Narodna in univerzitetna knjižnica, Ljubljana (NUK)
Naročanje gradiva za izposojo na dom
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi
  • Vloga metformina pri obravnavi bolnic s sindromom policističnih jajčnikov = The role of metformin in the treatment of patients with polycystic ovary syndrome
    Košir-Pogačnik, Renata, dr. med. ; Meden-Vrtovec, Helena
    Background Polycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting women of reproductive age in 10.20% under the American criteria and 15.22% under the European criteria. It ... is presented with disorders in the menstrual cycles, hirsutism, acne, alopecia and obesity. Nowadays, metformin drug has joined the traditional and established methods oftreatment that are mainly focused to prevention of the leading symptom (hirsutism or irregular periods or fertility problems). Metformin is a peroralanti-diabetic agent that increases insulin sensitivity. Insulin stimulates androgen secretion by the ovarian stroma and appears to affect the normal development of ovarian follicles by suppressing apoptosis and permitting the survival of follicles otherwise destined to disappear. The longterm sequelae of insulin resistance may be the development of insulin-dependent diabetes and dyslipidemia. Conclusions The results of meta-analysis and other studies confirm that metformin prevents the progress of insulin resistance, has a favourable impact on loosing weight and is effective in induction of ovulation, mainly in clomiphen resistant women.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 78, št. 3, mar. 2009, str. 137-141)
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - slovenski
    COBISS.SI-ID - 25605337

    Povezava(-e):

    Digitalna knjižnica Slovenije - dLib.si

Vnos na polico