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  • Encimi iz naddružine kratkoverižnih dehidrogenaz/reduktaz kot nove farmakološke tarče = Enzymes of the short-chain dehydrogenase/reductase superfamily s new pharmacological targets
    Brunskole Švegelj, Mojca ; Lanišnik-Rižner, Tea ; Stojan, Jure, 1956-
    Short-chain dehydrogenases/reductases (SDR) constitute a large protein family.Although they have several structural features in common, they act on ahighly diverse set of substrates. They are ... involved in metabolism of steroid hormones, fatty acids, alcohols, retinoids, prostaglandins and xenobiotics. Around 70 SDR members are identified within the human genome. In human body they participate in numerous distinct (patho)physiological processes, thus they are very interesting therapeutic targets for the treatment of genetic, hormone dependent and metabolic diseases like galactosemia, phenylketonuria, breast cancer, endometrium, prostate and colon cancer, dyslipidemia, obesity and arterial hypertension.
    Vir: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 60, št. 3, jul. 2009, str. 159-164)
    Vrsta gradiva - članek, sestavni del
    Leto - 2009
    Jezik - slovenski
    COBISS.SI-ID - 25713625

    Povezava(-e):

    Digitalna knjižnica Slovenije - dLib.si

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