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  • Biološka zdravila pri zdravljenju astme = Biologic drugs in asthma treatment
    Berce, Vojko ; Krajnc, Ivan, 1948- ; Potočnik, Uroš, 1969-
    Development of the new antiasthmatic drugs is directed ab ove all in the synthesis of the inhibitors of the proinflammatory cytokines and IgE antibodies. Several biologic drugs are tested for this ... purpose; most common ofthem are monoclonal antibodies or modified receptol-s. Experiments were alsodo ne with antiinflammatory cytokines, chemokine inhibitors, antilymphocytic antibodies, cell adhesion blockers and CpG oligonucleotides. The most promising drugs are those directed against interleukines IL-4, IL-S, IL-13, cytokine TNFa and IgE immunoglobulin. Humanized monoclonal antibody directed against immunoglobulin E binding site is the only biologic drug whichis already us ed in the asthma treatment. Better understanding of the molecular mechanisms of asthma leads to the identification of the new therapeutic targets.
    Vir: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 49, št. 1, mar. 2010, str. 11-18)
    Vrsta gradiva - članek, sestavni del
    Leto - 2010
    Jezik - slovenski
    COBISS.SI-ID - 26741721

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    Digitalna knjižnica Slovenije - dLib.si

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