Narodna in univerzitetna knjižnica, Ljubljana (NUK)
Naročanje gradiva za izposojo na dom
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi
  • Tesnostične pregrade v našem telesu = Tight junction barriers in our body
    Jezernik, Kristijan ; Erdani-Kreft, Mateja
    Tight junctions comprise a crucial part of epithelial barriers by forming a molecular pore like structure that encircles the apex of individual cells. They control the passage of small molecules ... between apical and basolateral compartments. Junctions are composed of a branching network of sealing strands. Each strand is formed from a row of transmembrane proteins namely occludin and claudins, embedded in both plasrna membranes, with extracellular domains joining one another direcdy. These associate with different peripheralmembrane proteins located on the intracellular side of plasrna membrane, which anchor the strands to the actin cytoskeleton. This overview gives a detailed survey about the proteins associated with tight junctions, their structure and functions including a wealth of the relevant literature. We summarize our knowledge about tight junction proteins in mammalian epithelial tisue and their involvement in some diseases. Their putative suitability as new targets for improving drug delivery is discussed.
    Vir: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 49, št. 1, mar. 2010, str. 51-62)
    Vrsta gradiva - članek, sestavni del
    Leto - 2010
    Jezik - slovenski
    COBISS.SI-ID - 26743001

    Povezava(-e):

    Digitalna knjižnica Slovenije - dLib.si

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