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Naturally occurring anti-E red-cell antibodies in a 3-month old infant = Naravna anti-E eritrocitna protitelesa prisotna pri trimesečnem otrokuŠimc, Mojca ; Rožman, Primož, 1954-Background: Before the transfusion of the red blood cells containing blood components is applied, pre-transfusion testing such as ABO, RhD and Kell bloodgrouping with a negative crossmatch is ... obligatory. This can be reduced toblood grouping only in infants less than 4 months of age, provided that the initial antibody screening test is negative. Only a few cases of antibody formation in such young infants have been described, the majority of them haveresulted from exposure to allogeneic transfusions. Case report: During thepre-transfusion testing, naturally occurring anti-E red blood cell antibodies were detected in a 3-month old male infant, who underwent surgery for atresia of the extra hepatic bile ducts followed by a bacterial infection.All immunohaematological tests were performed using the commercial gel column agglutination method, screening cells, RBC panel and enzyme-modified cells according to the manufacturerćs instructions. The passive transfer of anti-E antibodies with blood components and the transfer of the antibodies from the mother during pregnancy and also through lactation were excluded. Immunisation due to exposure to E antigen was ruled out by confirming the E-negativity of all the red blood cell units the infant had received and also by confirming the E-negativity of the mother. Conclusion: Although the naturally occurring anti-E red-cell antibodies are usually found in adults, we report here a case of a 3-month old infant, who had developed naturally occurring anti-E red cell antibodies.Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 79, št. 12, dec. 2010, str. 864-869)Vrsta gradiva - članek, sestavni delLeto - 2010Jezik - angleškiCOBISS.SI-ID - 27830489
Avtor
Šimc, Mojca |
Rožman, Primož, 1954-
Teme
Blood Grouping And Crossmatching |
Blood Component Transfusion |
Biliary Atresia |
Surgery |
Erythrocytes |
Isoantibodies |
Infant |
Igg |
Krvne skupine in navzkrižno določanje |
Biliarna atrezija |
Krvna sestavina, transfuzija |
Eritrociti |
Izoprotitelesa |
Dojenček |
IgG |
transfuzija krvi |
krvne skupine |
testiranje |
dojenčki |
protitelesa |
eritrocitna protitelesa
vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 79, št. 12, dec. 2010, str. 864-869)
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Rožman, Primož, 1954- | 12336 |
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