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  • Fibrinogen, dejavniki tveganja in zastopanost periferne arterijske okluzivne boezni pri sladkornih bolnikih = Fibrinogen, risk factors and prevalence of the peripheral arterial occlusive disease by diabetics
    Mlačak, Blaž ...
    Background. Recent epidemiologic studies have ascertained that the firbrinogenlevel is a significant risk factor for the development of atherosclerosis. Our research object was to find out the ... occurrence frequency of the heightened fibrinogen level and known risk factors for atherosclerosis in a group of diabetics. Furthermore, we intended to find out the occurrence frequency of the peripheral arterial occlusive disease in persons with risk factors. Methods. In the test group there were 138 diabetics at te age of 23 to 88, and among them 60 men and 78 women. The control group which consisted of 160 examinees without diabetes, among them 69 men and 91 women, was comparable to the test group age, sex and vocational pretentiousness. Menacingfactors were defined by knowncriteria, while we considered the fibrinogen level in blood over 3.0 g/L as heightened. The peripheral arterial occlusive disease on lower limbs was ascertained by the systolic blood pressure measuring by means of the supersonic Doppler detector. The differencein the menacing factors participation for atherosclerosis, and the heightened fibrinogen level between the test and the control group was tested by the c square test. Results. The peripheral arterial occlusive disease was found in 27.3% of diabetics, and in 8.8% of examinees in the control group. The difference is statistically significant (P<0.001). 52.2% of diabetics had the heightened fibrinogen level, 84.5% of the increased body weight, 65.5% of hypertension, and 76.4% of hyperlipidemia (cholesterol and triglycerides together). In the test group there was in comparison with the control group a significantly greater number of persons with the heightened fibrinogen level (P<0.001), hyperlipidemia (P<0.01), hypertension (P<0.01), and the increased body weight (P<0.05). (Abstract truncated at 2000 characters.)
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 67, št. 3, mar. 1998, str. 139-141)
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - slovenski
    COBISS.SI-ID - 7879897

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