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  • Congenital extrahepatic biliary atresia in children in Slovenia - epidemiological retrospective data = Prirojena atrezija zunajjetrnih žolčevodov pri otrocih iz Slovenije - epidemiološki retrospektivni podatki
    Fister, Petja ...
    Backg round: The objective of this study was to investigate the history, clinical, laboratory, imaging data and outcome of children with biliary atresia in Slovenia. Methods: In an epidemiological ... single-arm retrospective study health records of infants born in Slovenia between October 1996 and October 2011, who were diagnosed with biliary atresia at the University Childrenʼs Hospital, University Medical Centre Ljubljana, were reviewed. Epi-demiological data and outcomes of patients with biliary atresia in Slovenia were studied. Results: In the 15-year period, 16 cases of biliary atresia were confirmed (1/20000 newborns). Two thirds of patients in our cohort were females. One child had associated laterality malformation. The majority of patients were born in autumn and winter months. The affected newborns were born mature with appropriate birth measures and healthy, but most of them became jaundiced in the first days of life. Primary surgery was done in 11 children at median age of 70 days. Of those children in whom the surgery was unsuccessful, 13 (81 %) underwent liver transplantation in foreignsurgical centres. Median age at liver transplantation was 9 months, median time from Kasai operation to liver transplantation was 5 months. Medianfollow-up was 9.75 years (range 1.2-15.4). Conclusions: In Slovenia, theincidence of biliary atresia is low and biliary atresia splenic malformation very rare. The observed seasonal incidence might suggest the viral aetiology.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 82, št. 2, feb. 2013, str. 86-92)
    Vrsta gradiva - članek, sestavni del
    Leto - 2013
    Jezik - angleški
    COBISS.SI-ID - 800684

    Povezava(-e):

    http://ojs.szd.si/index.php/vestnik/article/view/1749
    Digitalna knjižnica Slovenije - dLib.si

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