Narodna in univerzitetna knjižnica, Ljubljana (NUK)
Naročanje gradiva za izposojo na dom
Naročanje gradiva za izposojo v čitalnice
Naročanje kopij člankov
Urnik dostave gradiva z oznako DS v signaturi
  • Mycological examination in pachyonychia congenita
    Kansky, Aleksej ...
    Introduction. Pachyonychia congenita (PC) is a hereditary disorder of keratinization characterized by extremely thickened nails, follicular hyperkeratosis, insular palmoplantar keratoderma and ... thickened, whitish lingual and buccal mucosa sometimes involving also gingivae. It was established during the last few years that this disorder is due to mutations of keratin genes. The additional role of yeasts in the pathogenesis of PC was sometimes questioned, however no systemic study could be traced in the literature. Methods. mycologic investigations of nails and insular keratoses were carried out in eight Slovenian patients with PC-1: direct microscopy and cultivation on Sabouraud's dextrose agar. In all these patients the keratin mutations had been defined. Results. Candida species (Cand sp) were isolated from fingernails in two and Aspergillus sp in another patient. From toenails Cand sp was isolated in 2 and Rodotorula sp in another patient. From the keratinous material from the soles Trinchophyton mentagrophytes was isolated in two patients and Cand sp in another. Conclusion. Detection of Cand sp, Aspergillus sp or Rodotorula sp, spores in just a few patients is considered to be an accompanying phenomenon.
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - angleški
    COBISS.SI-ID - 8099289