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  • Nekonjugirana hiperbilirubinemija pri novorojenčku = Unconjugated hyperbibirubinemia in term newborns
    Groleger, Katja ; Bratanič, Borut, 1947- ; Veličković Perat, Milivoj
    The paper presents the metabolism of bilirubin and consequences of its toxic effect on new-born's brain. Increased production or decreased excretion of bilirubin, or a combination of both, may be the ... cause of neonatal jaundice. Affer passing across the blood-brain barrier, bilirubin is deposited in some regions of the brain. Unconjugated and unbound bilirubin is toxic, and is especially harmful to the brain of a new-borns. The mechanism of its toxicity is not yet understood, but it is well known that bilirubin can affect enzymes and cell membranes. The clinical picture of bilirubin encephalopathy has threephases. Late sequelae are offen manifested as cerebral palsy, deafness and mental retardation. The paper gives several recommendations for the management of severe jaundice and prevention of bilirubin encephalopathy.
    Vir: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 37, [št.] 3, sep. 1998, str. 355-366)
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - slovenski
    COBISS.SI-ID - 9229273

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    Digitalna knjižnica Slovenije - dLib.si

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