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  • Prikaz, ugotavljanje in zdravljenje nekaterih imunskih krvnih bolezni = Presentation, diagnosis and treatment of some immunohematologic diseases
    Černelč, Peter
    Clinical hematology is the field of medicine most closely related to immunology, since pathologically aftered cells and other components of the immune response circulating in the blood form the basis ... of some hematological diseases. The author presents a female patient with acute lymptioblastic leukemia, anodier female patient suffering from autoimmune henpytic anemia, immune thrombocytopenia and pemicious anemia, and a male patient treated for aplastic anemia. Disorders characterized by malignant proliferation of cells involved in the immue response include acute lymphoblastic leukemia, malignantlymphomas and malignant immunoproliferative diseases. A patho- logically aftered immune response is associated with the appearance of antibodies which may be directed against erylhrocytes, platelets, neutrophils,coagulation factors, hemopoietic progenitor cells, parietal cells of the gastric mucosa or the intrinsic factor. The detection and, in particular, confirmation of an immune disorder often require the use of socalled immunological tests, which are based on individual reactions of the immune response. For the diagnosis of leukemias, malignant lymphomas and, in particular, subtypes of acute lymphoblastic leukemia, immunophenotyping of surface and cytoplasmic immunoglobulins is performed using flow cytometry. Oneof the oldest immunological investigations is the Coombs test for confirmation of autoimmune hemolytic anemia. Immune disorders are treated moreor less successtully with various immunosuppressive agents, such as corticosteroids, antilymphocyte globulin and cyclosporin. Only good knowledge of immune disorders and the methods used for their diagnosis can guarantee reliable prediction of the course of illness and its successful management.
    Vir: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 37, [št.] 3, sep. 1998, str. 381-390)
    Vrsta gradiva - članek, sestavni del
    Leto - 1998
    Jezik - slovenski
    COBISS.SI-ID - 9229785

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    Digitalna knjižnica Slovenije - dLib.si

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