-
Hormon stradanja fibroblastni rastni dejavnik 21 - novo zdravilo za debelost in metabolni sindrom? = Fasting hormone fibroblast growth factor 21 - new therapy for obesity and metabolic syndrome?Fon Tacer, KlementinaIncreasing prevalence of metabolic diseases is alarming and highlights the need for more effective and safer therapies. Current recommendations for therapy for metabolic syndrome focus on corrections ... of the individual components. Fibrates are used to treat hyperlipidemia as a predisposing factorto metabolic syndrome and cardiovascular disease. Fibrates mediate theirtherapeutic effects through the peroxisome proliferator-activated receptor alpha (pPARa). PPARa acts as a transcriptional activator of genes involved in lipolysis and ketone body synthesis. The majority of PPARa effectsare mediated by recently discovered starvation hormone - fibroblast growth factor FGF21. Recent evidence from several animal studies indicates that FGF21 induces numerous beneficial metabolic changes without apparent adverse effects. These results suggest that FGF21 could be a novel and attractive drug candidate for the treatment of cardiovascular disease, obesity, and type 2 diabetes.Vir: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 60, št. 5, 2009, str. 251-255)Vrsta gradiva - članek, sestavni delLeto - 2009Jezik - slovenskiCOBISS.SI-ID - 26146265
Avtor
Fon Tacer, Klementina
Teme
Diabetes Mellitus, Non-Insulin-Dependent |
Hyperlipidemia |
Drug Therapy |
Fibroblast Growth Factor |
Starvation |
Obesity |
Energy Metabolism |
Dietary Fats |
Hiperlipidemija |
Fibroblastni, rastni faktor |
Debelost |
Sladkorna bolezen, ne-inzulin-odvisna |
Stradanje |
Energetska presnova |
Dietne maščobe
![loading ... loading ...](themes/default/img/ajax-loading.gif)
vir: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Letn. 60, št. 5, 2009, str. 251-255)
![loading ... loading ...](themes/default/img/ajax-loading.gif)
![loading ... loading ...](themes/default/img/ajax-loading.gif)
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|---|
Fon Tacer, Klementina | 20347 |
Izberite prevzemno mesto:
Prevzem gradiva po pošti
Obvestilo
Gesla v Splošnem geslovniku COBISS
Izbira mesta prevzema
Mesto prevzema | Status gradiva | Rezervacija |
---|
Prosimo, počakajte trenutek.