E-viri
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Wullich, B; Koch, B; Schwarz, M; Lindemann, U; Pfreundschuh, M; Zang, K D
Cancer genetics and cytogenetics, 09/1993, Letnik: 69, Številka: 2Journal Article
In very rare patients tetrasomy of chromosome 8 is observed as the only karyotypic event. We present a 74-year-old man with acute monocytic leukemia (FAB M5) displaying 46,XY/48,XY, +8, +8 in unstimulated bone marrow cells. The patient died 2 weeks after diagnosis. Tetrasomy 8 appears to identify a subgroup of acute nonlymphocytic leukemia. It may indicate a poor prognosis.
