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Lachmann, Helen J; Kone-Paut, Isabelle; Kuemmerle-Deschner, Jasmin B; Leslie, Kieron S; Hachulla, Eric; Quartier, Pierre; Gitton, Xavier; Widmer, Albert; Patel, Neha; Hawkins, Philip N
New England journal of medicine/The New England journal of medicine, 06/2009, Letnik: 360, Številka: 23Journal Article
The cryopyrin-associated periodic syndrome (CAPS) is associated with an overproduction of interleukin-1. Canakinumab, an anti–interleukin-1β monoclonal antibody, was given to 35 patients with CAPS and was found to induce remission in most of the patients. The cryopyrin-associated periodic syndrome (CAPS) is associated with an overproduction of interleukin-1. Canakinumab, an anti–interleukin-1β monoclonal antibody, was given to patients with CAPS and was found to induce remission in most of the patients. The cryopyrin-associated periodic syndrome (CAPS) comprises a spectrum of apparently distinct, rare, inherited inflammatory disorders of increasing severity, including the familial cold autoinflammatory syndrome, the Muckle–Wells syndrome, and neonatal-onset multisystem inflammatory disorder (also known as the chronic infantile neurologic, cutaneous, and articular syndrome). Patients with these disorders have severe fatigue, fever, and influenza-like myalgia from infancy, together with chronic anemia and inflammation of the skin, eyes, bones, joints, and meninges. Clinical features include rash, conjunctivitis, arthritis, chronic meningitis, sensorineural deafness, and intellectual impairment. Systemic AA amyloidosis that causes renal failure and usually results in death within 5 to 10 years . . .
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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