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  • Minimal introns are not "junk"
    Minimal introns are not "junk"
    Yu, Jun; Yang, Zhiyong; Kibukawa, Miho; Paddock, Marcia; Passey, Douglas A; Wong, Gane Ka-Shu

    Genome research 12, Številka: 8
    Journal Article

    Intron-size distributions for most multicellular (and some unicellular) eukaryotes have a sharp peak at their "minimal intron" size. Across the human population, these minimal introns exhibit an abundance of insertion-deletion polymorphisms, the effect of which is to maintain their optimal size. We argue that minimal introns affect function by enhancing the rate at which mRNA is exported from the cell nucleus.

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