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Grifoni, Elisa; Bini, Chiara; Signorini, Ira; Cosentino, Eleonora; Micheletti, Irene; Dei, Alessandro; Pinto, Gabriele; Madonia, Elisa Maria; Sivieri, Irene; Mannini, Marianna; Baldini, Mariella; Bertini, Elisabetta; Giannoni, Sara; Bartolozzi, Maria Letizia; Guidi, Leonello; Bartalucci, Paola; Vanni, Simone; Segneri, Antonio; Pratesi, Alessandra; Giordano, Antonio; Dainelli, Francesca; Maggi, Francesca; Romagnoli, Mario; Cioni, Elisa; Cioffi, Elisa; Pelagalli, Giulia; Mattaliano, Chiara; Schipani, Elena; Murgida, Giuseppe Salvatore; Di Martino, Stefania; Sisti, Eleonora; Cozzi, Andrea; Francolini, Valentina; Masotti, Luca
The Neurologist (Baltimore, Md.), 05/2023, Letnik: 28, Številka: 3Journal Article
Few data exists on predictive factors of hemorrhagic transformation (HT) in real-world acute ischemic stroke patients. The aims of this study were: (i) to identify predictive variables of HT (ii) to develop a score for predicting HT. We retrospectively analyzed the clinical, radiographic, and laboratory data of patients with acute ischemic stroke consecutively admitted to our Stroke Unit along two years. Patients with HT were compared with those without HT. A multivariate logistic regression analysis was performed to identify independent predictors of HT on CT scan at 24 hours to develop a practical score. The study population consisted of 564 patients with mean age 77.5±11.8 years. Fifty-two patients (9.2%) showed HT on brain CT at 24 hours (4.9% symptomatic). NIHSS score ≥8 at Stroke Unit admission (3 points), cardioembolic etiology (2 points), acute revascularization by systemic thrombolysis and/or mechanical thrombectomy (1 point), history of previous TIA/stroke (1 point), and major vessel occlusion (1 point) were found independent risk factors of HT and were included in the score (Hemorrhagic Transformation Empoli score (HTE)). The predictive power of HTE score was good with an AUC of 0.785 (95% CI: 0.749-0.818). Compared with 5 HT predictive scores proposed in the literature (THRIVE, SPAN-100, MSS, GRASPS, SITS-SIC), the HTE score significantly better predicted HT. NIHSS score ≥8 at Stroke Unit admission, cardioembolism, urgent revascularization, previous TIA/stroke, and major vessel occlusion were independent predictors of HT. The HTE score has a good predictive power for HT. Prospective studies are warranted.
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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