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Vznik in razvoj karcinoma v luči spoznanj molekularne genetikeFerluga, Dušan, 1934- ...Cancer is basically the result of accumulating genetic damage. Carcinogenesis in humans is a long-term multistage process which includes initiation, promotion and progression. Initiation is ... characterized by mutation of genes regulating cell growth, replication, differentiation, and apoptosis. Cell proliferation implicated in promotion by epigenetic events enables fixation ofgenetic damage. Clonal expression of cells acquiring a selective growth advantage plays an important role in carcinogenesis. Progression primarily involves genes regulating cell adhesion molecules and production of proteases.Steadily increasing knowledge about growth factors, signal transduction pathways, and cancer genes contributes to the better understanding of carcinogenesis.Source: Tumorji ledvic : v počastitev 75. obletnice Medicinske fakultete in Univerze v Ljubljani (1994, Str. 165-183)Type of material - conference contributionPublish date - 1994Language - slovenianCOBISS.SI-ID - 160729
source: Tumorji ledvic : v počastitev 75. obletnice Medicinske fakultete in Univerze v Ljubljani (1994, Str. 165-183)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Ferluga, Dušan, 1934- | 02273 |
Vodovnik, Aleksandar | 15471 |
Gale, Nina | 02127 |
Kambič, Vinko | 00304 |
Source: Personal bibliographies
and: SICRIS
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